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专题浏览
Depression and the risk for cardiovascular diseases: systematic review and meta analysis(抑郁症和心血管疾病风险:系统综述和荟萃分析)
背景:在老年人群抑郁症和心血管疾病均较常见。抑郁症被怀疑是促使冠心病发作的独立风险因子,然而其影响程度,是否还会促发其他的循环系统疾病仍未可知。 目的:评估抑郁症作为独立风险因子对促发各种心血管疾病(CVD)的风险,并揭示多相性和方法学质量的影响...

抑郁状态时失眠的病理生理机制及其处理 [综述87篇参考文献]
抑郁症病人常报告有睡眠问题,流行病学证据提示失眠可能是抑郁发作的前兆,而且,失眠与生活质量及社会功能受损相关。许多研究表明,患有慢性睡眠问题的病人常有情绪障碍,有效处理抑郁症病人的失眠能明显改善抑郁情绪。由于可能有许多不同的原因造成失眠以及...
焦虑症、抑郁症和失眠 [综述130篇参考文献]
本文综述了治疗抑郁症、焦虑和失眠的不同方法。治疗抑郁症的方法包括:圣约翰草、L-色氨酸、5-羟色氨酸、S-腺苷甲硫氨酸、脱氢表雄酮、叶酸、锻炼、针灸和沉思等;治疗焦虑症的方法有:卡哇(kava)、锻炼、放松治疗以及针灸等...

失眠的维持治疗:从有关抑郁症的文献中我们能学到什么?[综述106篇参考文献]
失眠和抑郁症是常见的公共卫生问题。如果不及时治疗,任其发展与存在,其患病率很高。目前有证据表明,抑郁症长期维持治疗疗效肯定,但失眠是否需要维持治疗、其安全性和有效性如何仍有待于循征医学的研究。许多病人和医生不主张长期药物治疗失眠...
失眠、抑郁症和衰老:老年人睡眠与情绪相互作用的评估 [综述39篇参考文献]
在流行病学、临床表现、神经生物学和治疗等多方面,失眠和抑郁症是两者有许多重叠,相互之间难以截然分开。这种相关在老年人睡眠改变中显得尤为突出,流行病学资料显示,情绪抑郁是失眠的最危险因素之一。不过,近期研究提示,这种相关可能是相互的...

有关胆碱酯酶抑制剂多奈哌齐(Donepezil)治疗痴呆的系统文献综述
目的:客观评价应用多奈哌齐治疗阿尔茨海默病(AD)的科学证据。方法:从MEDLINE和EMBASE数据库中检索到10项多奈哌齐随机双盲与安慰剂对照临床试验,并进行系统文献综述。按照标准目录逐条对10项研究的方法学标准进行评估...

银杏叶提取物Ginkgo biloba和胆碱酯酶抑制剂治疗痴呆的比较:基于cochrane协作网的meta分析结果的综述
数据来自Cochrane协作网对银杏叶提取物、多奈哌齐、rivastigmine 及加兰他敏在改善痴呆病人认知功能方面进行meta分析,评估治疗6个月后的结果。结果发现,胆碱酯酶抑制剂的疗效一致性比银杏叶提取物好,特别是多奈哌齐(5 mg和10 mg),rivastigmin(6-12 mg)...

A review of the acute subjective effects of MDMA/ecstasy (综述:急性期服用摇头丸的主观感觉体验)
目的:虽然最近有几篇文献总结了慢性服用摇头丸相关的神经精神病的影响,但对服用摇头丸急性期的主观感觉尚无全面研究。方法:本次研究回顾了患者急性期一些主观感觉的患病率、强度和持续时间,24名参与研究者自报相关数据或者提供摇头丸效应强度资料...


文献服务
The myelin-pathogenesis puzzle in schizophrenia: a literature review
Schizophrenia is a serious and disabling mental disorder with symptoms such as auditory hallucinations, disordered thinking and delusions, avolition, anhedonia, blunted affect and apathy. In this review article we seek to present the current scientific findings from lin...

A Review of Brief Medication-Adherence Instruments Used in Patients with Schizophrenia and Bipolar Disorder
Medication nonadherence is common,and patients suffering from psychiatric disorders are the least likely to adhere to pharmacotherapy as compared to patients who are receiving medication for physical symptoms associated with nonpsychiatric disorders.Nonadherence is espe...

Depression and anxiety in obstructive sleep apnea syndrome: a review
Objective - To provide an update on recent research on depression and anxiety in obstructive sleep apnea syndrome (OSAS).Methods - A review was carried out on reports drawn from MEDLINE and PSYCHLIT (January 1995-June 2006) and identified from their list of references. ...

Physical illness and schizophrenia: a review of the literature
Objective The lifespan of people with schizophrenia is shortened compared to the general population. We reviewed the literature on comorbid physical diseases in schizophrenia to provide a basis for initiatives to fight this unacceptable situation.Method We searched MEDL...

Risk factors, prevalence, and treatment of anxiety and depressive disorders in Pakistan: systematic review
OBJECTIVES: To assess the available evidence on the prevalence, aetiology, treatment, and prevention of anxiety and depressive disorders in Pakistan. DESIGN: Systematic review of published literature. STUDIES REVIEWED: 20 studies, of which 17 gave prevalence estimates a...

Contact with mental health and primary care providers before suicide: a review of the evidence
OBJECTIVE: This study examined rates of contact with primary care and mental health care professionals by individuals before they died by suicide. METHOD: The authors reviewed 40 studies for which there was information available on rates of health care contact and exami...

Augmentation strategies for treatment-resistant depression a literature review
Background The large majority of depressed patients fail to remit on the first antidepressant prescribed. These patients with residual symptoms have higher relapse rates and poorer outcomes than those who remit. Treatment-resistant depression (TRD) is a therapeutic chal...

Anterior cingulate volumes in schizophrenia: A systematic review and a meta-analysis of MRI studies
Objectives Several MRI studies have investigated the anterior cingulate in schizophrenia, as this is a key region for emotional processing and higher executive performances. A systematic review of structural MRI studies and a meta-analysis were conducted to explore whet...

Coping with hallucinated voices in schizophrenia: A review of self-initiated strategies and therapeutic interventions
This article reviews the state of knowledge about strategies used by people with a diagnosis of schizophrenia to cope with hallucinated voices, and considers the role of coping in psychological treatments for persisting symptoms. The use of self-initiated (‘natural') co...

Impaired recognition and expression of emotional prosody in schizophrenia Review and meta-analysis
Background Deficits in emotion processing may be one of the most pervasive disturbances in schizophrenia that may contribute to social isolation. In this report we focus on vocal emotion processing. This function bears upon two corner stones of social functioning, langu...

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