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社交焦虑和失眠：抑郁症状的调节作用(Social anxiety and insomnia: the mediating role of depressive symptoms)
焦虑通常会伴发失眠。社交焦虑障碍是最常见的焦虑障碍之一，而且社交焦虑的患者可能特别容易受失眠的影响。然而，对于这种相关性方面的实验工作目前进行的还很少。本研究使用双变量的关系，在大学生样本人群(n=176)中来验证社交焦虑是否与失眠有关...

Insomnia has distinct relationships with anxiety disorders and depression(失眠和焦虑症与抑郁症的关系密切)
研究人员已经阐明了失眠症、焦虑症和抑郁症发展的自然模式，发现与抑郁症相比较，失眠症和焦虑症之间存在着相互独立，又有可能有明显的指向性关联。 “对青少年人群而言，失眠症和焦虑症之间指向关联的优势模式是由焦虑而引发失眠...

原发性失眠中应激症状和抑郁症状是睡眠的相关因素
目的：以前对失眠病人的研究很少评估相关的脑电图情况。该预初研究评估了慢性失眠者的应激和抑郁症状与其失眠主诉和睡眠脑电变化之间的相关程度。方法：对象是符合美国精神障碍诊断和统计手册第4版（DSM-IV）中原发性失眠诊断标准的14名健康成人...

抑郁状态时失眠的病理生理机制及其处理 [综述87篇参考文献]
抑郁症病人常报告有睡眠问题，流行病学证据提示失眠可能是抑郁发作的前兆，而且，失眠与生活质量及社会功能受损相关。许多研究表明，患有慢性睡眠问题的病人常有情绪障碍，有效处理抑郁症病人的失眠能明显改善抑郁情绪...

失眠、抑郁和死亡的关系：对社区老人12年的随访
研究目的是调查失眠的自然规律，以及与抑郁、死亡的关系。1983年随机选取1870名对象（年龄在45岁至65岁），回答一份关于睡眠和健康的问卷，1995年对1604名存活者中的1244人（77.6%）再调查，回答一份新问卷（大部分问题与第一次问卷相同）...

焦虑症、抑郁症和失眠 [综述130篇参考文献]
本文综述了治疗抑郁症、焦虑和失眠的不同方法。治疗抑郁症的方法包括：圣约翰草、L-色氨酸、5-羟色氨酸、S-腺苷甲硫氨酸、脱氢表雄酮、叶酸、锻炼、针灸和沉思等；治疗焦虑症的方法有：卡哇（kava）、锻炼、放松治疗以及针灸等；治疗失眠的方法包括：缬草制剂、褪黑激素、甘菊、西番莲、锻炼、针灸和行为治疗（如睡眠限制、刺激控制、放松和睡眠卫生）等。（复旦大学上海医学院精神卫生学系：张红霞，陈华编译，季建林审校）

失眠的中年妇女中应激暴露、心理痛苦和生理应激的激活
目的：比较心理生理型（PP型）或主观型（SO型）失眠或不失眠的中年妇女多导睡眠仪（PSG）描记的睡眠形式，并讨论在应激暴露、心理痛苦和生理应激激活方面是否存在差异。方法：为期1周，监测妇女的睡眠，收集尿样，并完成问卷。根据自我报告的睡眠质量和PSG的睡眠效率...

癌症化疗病人的失眠、疲乏、焦虑、抑郁和生活质量
研究目的是：（a）调查癌症化疗病人发生失眠、疲乏和焦虑、抑郁症状的比例，及其与心理因素的关系； (b)这些症状及其心理问题与生活质量的相关性。基本假设是不愉快症状理论（The Theory of Unpleasant Symptoms）。样本264例，均为正在接受化疗的癌症病人...

1950年至1960年间荷兰女性杂志'Margriet'上登载关于抑郁、焦虑和失眠的医学信息分析 [荷兰语]
20世纪后50年代中期，媒体上开始登载有关健康和医药的报道，对于帮助人们认识、定义和应对日常健康问题起到了重要的健康促进作用。以医药知识普及介绍为主来突出供方市场，同时提供医药新进展的信息和简单的治疗方法。尽管是女性杂志，但也很重视图文并茂形式的医药知识普及...

失眠的维持治疗：从有关抑郁症的文献中我们能学到什么？[综述106篇参考文献]
失眠和抑郁症是常见的公共卫生问题。如果不及时治疗，任其发展与存在，其患病率很高。目前有证据表明，抑郁症长期维持治疗疗效肯定，但失眠是否需要维持治疗、其安全性和有效性如何仍有待于循征医学的研究。许多病人和医生不主张长期药物治疗失眠，或许与缺乏相关证据有关...

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Insomnia in Young Men and Subsequent Depression
The Johns Hopkins Precursors Study, a long-term prospective study, was used to study the relation between self-reported sleep disturbances and subsequent clinical depression and psychiatric distress. A total of 1,053 men provided information on sleep habits during medic...

Sleep-Related Functioning in Euthymic Patients With Bipolar Disorder, Patients With Insomnia, and Subjects Without Sleep Problems
OBJECTIVE: The authors investigated sleep-related functioning in euthymic patients with bipolar disorder. METHOD: Euthymic patients with bipolar disorder (N=20), patients with insomnia (N=20), and subjects with good sleep (N=20) were compared on data from interviews and...

The association of insomnia with anxiety disorders and depression-Exploration of the direction of risk
The purpose of this study is to explore the direction of the association between insomnia and anxiety disorders and major depression among a community-based sample of adolescents to better understand their potential etiologic relationships. Data come from a community-ba...

Paroxetine treatment of primary insomnia in older adults.
The goal of this study was to test the efficacy of paroxetine for primary insomnia in older adults. METHODS: Adults over age 55 with primary insomnia were randomly assigned to six weeks of double-blind treatment with paroxetine (N = 14) or placebo (N = 13...

Antidepressant treatment of the depressed patient with insomnia
Sleep disturbances are an integral part of depressive disorder. As such, they are a part of all contemporary sets of diagnostic criteria for major depression and of all major symptom-based rating scales for depression. Insomnia is a particularly frequent complaint, and ...

Eszopiclone, a Nonbenzodiazepine Sedative-Hypnotic Agent for the Treatment of Transient and Chronic Insomnia
OBJECTIVE: This paper reviews the pharmacologic and pharmacokinetic properties, clinical efficacy, and safety profile of the nonbenzodiazepine cyclopyrrolone agent eszopiclone in the management of adult patients with insomnia. METHODS: Recent studies, abstracts, reviews...

Depression, Night Terrors, and Insomnia Associated With Long-Term Intrathecal Clonidine Therapy
Intraspinal clonidine is an effective adjunct to intrathecal/epidural opioid administration. We report a case of neuropathic pain treated with intraspinal analgesics in which depression, insomnia, and night terrors developed in association with intraspinal clonidine...

social anxiety and insomnia the mediating role of depressive symptoms
Anxiety is commonly associated with insomnia. Given that social anxiety disorder is one of the most prevalent anxiety disorders, socially anxious individuals may be particularly vulnerable to insomnia. However, there is currently very little empirical work on this relat...

Social anxiety and insomnia: the mediating role of depressive symptoms
Anxiety is commonly associated with insomnia. Given that social anxiety disorder is one of the most prevalent anxiety disorders, socially anxious individuals may be particularly vulnerable to insomnia. However, there is currently very little empirical work on this relat...