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专题浏览
惊恐障碍和广场恐惧症在普通门诊治疗的疗效
目的:认知治疗(CBT)是在最近的60年发展起来的。已经有多个临床试验证明了其疗效(美国精神病协会,1998)。但是在普通门诊并没有认识到这种治疗是行之有效的。该研究的目的就在于验证经验上有效的CBT治疗对惊恐障碍(伴随或不伴随广场恐惧症)在普通门诊中的疗效...

改善老年共病躯体疾病患者的抑郁后果
抑郁症是老年常见疾病,并且往往与多种慢性疾病并存,使得诊断和治疗复杂和困难。该研究旨在明确抑郁症病人共病多种躯体疾病与否对综合抗抑郁治疗的影响。研究对象为参加促进情绪改善合作治疗项目(Improving Mood-Promoting Access to Collaborative Treatment,IMPACT)的美国8个卫生保健机构下属的18个初级保健中心,分布于5个州,共1801例老年人(> 或 =60岁),时间为1999年7月到2001年8月,为随机对照..

临床实践中对皮肤病患者的身心评估
背景:皮肤病患者中出现精神障碍的比例较高,许多研究发现,精神活动和皮肤疾病之间存在复杂的相互影响。本研究旨在对不同人种的皮肤病患者进行系统的社会心理学评估,内容包括生活质量、精神疾病情况(DSM-IV),以及与身心症状相关的心理状况(参照心身研究诊断标准DCPR)等。 方法:共545例皮肤病住院患者(年龄18-65岁),其中包括痴呆和认知功能受损的患者...


文献服务
Physical illness and schizophrenia: a review of the literature
Objective The lifespan of people with schizophrenia is shortened compared to the general population. We reviewed the literature on comorbid physical diseases in schizophrenia to provide a basis for initiatives to fight this unacceptable situation.Method We searched MEDL...

Early cognitive-behavioural therapy for post-traumatic stress symptoms after physical injury. Randomised controlled trial
BACKGROUND: Early single-session psychological interventions, including psychological debriefing following trauma, have not been shown to reduce psychological distress. Longer early psychological interventions have shown some promise. AIMS: To examine the efficacy of a ...

Neurological soft signs and minor physical anomalies in patients with schizophrenia and related disorders, their first-degree biological relatives, and non-psychiatric controls
Background: Subtle neurological impairments and inconsequential minor anomalies of the face and limbs are manifestations of neurodevelopmental and ontogenic abnormalities that are consistently found at higher rates in individuals with schizophrenia compared to healthy c...

Effects of physical exercise on depression, neuroendocrine stress hormones and physiological fitness in adolescent females with depressive symptoms
Background: Regular physical exercise may improve a variety of physiological and psychological factors in depressive persons. However, there is little experimental evidence to support this assumption for adolescent populations. We conducted a randomized controlled trial...

DRUGS AS MATERIALS: VALUING PHYSICAL FORM IN DRUG DISCOVERY
Traditionally, potency and selectivity (and to some extent metabolism) have been the key parameters to consider in the process of discovering new drug candidates. Recently, heads of research and CEOs have been learning a new reality: drugs can move around...

MOOD, ANXIETY, AND PHYSICAL ILLNESS
This research review examines the recent articles that have investigated the relationship between mood, anxiety, and physical illness (e.g., asthma, autoimmune disorders, cancer, cardiovascular disease, obesity, and sexual dysfunction). There is growing evidence of an o...

Effect of antenatal exposure to paroxetine (Paxil) on growth and physical maturation of mice offspring
Objective Our purpose was to determine, in a placebo-controlled manner, whether antenatal exposure to paroxetine affected long-term growth and physical maturation of mice offspring. Methods Forty-one CD-1 mice consumed paroxetine (n = 21) or a placebo (n...

A Review of its Therapeutic Potential in the Treatment of Depression Associated with Physical Illness
Fluoxetine is a potent and selective inhibitor of neuronal serotonin (5-hydroxytryptamine) reuptake. Fluoxetine reduces food, energy and carbohydrate intake and increases resting energy expenditure, which may account for the moderate and transient bodyweight loss observ...

Depression in older adults exploring the relationship between goal setting and physical health
Depression in older adults is associated with a decreased quality of life, increased physical and emotional suffering and an increased risk of death and is often associated with declining physical health. Older people with physical illness have higher rates of depressio...

Depression in older adults- exploring the relationship between goal setting and physical health
Depression in older adults is associated with a decreased quality of life, increased physical and emotional suffering and an increased risk of death and is often associated with declining physical health. Older people with physical illness have higher rates of depressio...

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