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| Treatment of negative symptoms of schizophrenia using repetitive transcranial magnetic stimulation in a double-blind randomized controlled study |
| OBJECTIVE : To verify whether high-frequency rTMS applied above the area of the left prefrontal cortex in 15 stimulation sessions with maximum stimulation intensity is able to modify negative symptoms of schizophrenia in a double-blind, randomized controlled study. METHODS : Twenty-two patien |
| Blood pressure heart rate and anxiety in schizophrenia |
| Anxiety may worsen outcome in psychotic disorders. We assessed anxiety in 44 acutely psychotic subjects and found a positive association with heart rate and blood pressure. Risperidone treatment reduced anxiety but increased heart rate. We concluded that anxiety may adversely affect cardiovascular |
| Reduction in event-related alpha attenuation during performance of an auditory oddball task in schizophrenia |
| EEG frequency-domain analyses have demonstrated that cognitive performance produces a reduction in alpha activity, i.e., alpha attenuation, such as event-related desynchronization (ERD), reflecting brain activation. To examine whether schizophrenic patients have abnormalities in frequency-domain, e |
| Poor P50 Suppression Among Schizophrenia Patients and Their First-Degree Biological Relatives |
| OBJECTIVE : This studys goal was to replicate the finding that family members of schizophrenia patients show poor P50 suppression during a paired-click auditory evoked response paradigm. METHOD : The paired-click paradigm was used to test 44 schizophrenia patients, 60 of their clinically unaf |
| Plasma homocysteine, folate and B12 in chronic schizophrenia |
| Elevated plasma levels of the amino acid homocysteine have been associated with schizophrenia, particularly in young male patients. Among other factors, low folate and vitamin B12 levels have been implicated in the increase in homocysteine. In order to investigate this association, we determined pl |
| Multiple Dimensions of Schizotypy in First Degree Biological Relatives of Schizophrenia Patients |
| Considerable research has been devoted to identifying individuals predisposed to schizophrenia, with much of the effort devoted to identifying the personality characteristics of the biological relatives of schizophrenia patients. Although resource-consuming interviews have yielded promising results |
| Frequency and predictive values of first rank symptoms at baseline among 362 young adult patients with first-episode schizophrenia Results from the Danish OPUS study |
| AIM : To investigate the frequency of the Schneiderian First Rank Symptoms (FRSs) in a representative group of patients with first-episode schizophrenia and to analyse the predictive value of these symptoms in relation to psychopathology, work situation, depression, dependency and admission after |
| Familial liability and schizophrenia phenotypes-A polydiagnostic approach |
| BACKGROUND : There are conflicting results about the correspondence between the diagnostic phenotype of schizophrenia and genetic factors. Using a polydiagnostic approach we examined the relationship between familial liability and alternative schizophrenia phenotypes. METHODS : The sample com |
| Establishment of Diagnostic Validity in Psychiatric Illness Its Application to Schizophrenia |
| A method for achieving diagnostic validity in psychiatric illness is described,consisting of five phases:clinical description,labora-torystudy,exclusion of other disorders,follow-up study,and family study.The method was applied in this paper to patients with the diagnosis of schizophrenia,and it w |
| Effectiveness,safety,and tolerability of ziprasidone for treating schizophrenia patients undergoing usual care-A 12-month,open-label,flexible-dose,naturalistic observational trial |
| OBJECTIVE : This is a first report from a long-term study aimed to evaluate efficacy, safety, tolerability, cognitive functioning, and quality of life outcomes during ziprasidone treatment of chronic schizophrenia patients in the "real-world". METHOD : Seventy clinically unstable schizophre |
| Distributed Disturbances in Brain Structure and Function in Schizophrenia |
| Models of the nature of brain dysfunction in major psychiatric disorders haveevolved substantially over the past several decades in parallel with (if lagging some-what behind) the progression in knowledge resulting from investigations of the bio-logical mechanisms that contribute to normal cogniti |
| Traumatic Life Events and PTSD Among Women With Substance Use Disorders and Schizophrenia |
| Traumatic Life Events and PTSD Among Women With Substance Use Disorders and Schizophrenia Jean S. Gearon, Ph.D. Stacey I. Kaitman, Ph.D. Clayton Brown, Ph.D. Aim S. Bellad? Ph.D. Objcclire: l'he authors assessed the 1)reale11ct' of traumatic life ents and posttrauinatic stress disorder P1'SD) |
| A comprehensive assessment of gray and white matter volumes and their relationship to outcome and severity in schizophrenia |
| Preliminary data suggest an association of posterior cortical gray matter reduction with poor outcome in schizophrenia. We made a systematic MRI assessment of regional gray and white matter volumes, parcellated into 40 Brodmanns areas, in 104 patients with schizophrenia (51 with good outcomes, 53 w |
| Working memory in siblings of schizophrenia patients |
| Available online at www.scencedirectcorn ..‘ C 1Y .i- SCHIZOPHRENIA ? JclenceLJlr&I. RFSFARCH ELSEVIER schtzophtenia Reacarch 95(2007)70-75 :1 -.evicr.coin'bcatesc hn \VOrking memory in siblings of schizophrenia patients Neus Barrantes-Vidal a,b,*, I, Man Aguilera a, I Silvia Campanera c,d Mar |
| Working memory dysfunction in schizophrenia compared to healthy controls and patients with depression |
| Neurolmage wwwelaevia.ceaniceste/ynim Ncwohnagc 35 (2007) 1551—156 Working memory dysfunction in schizophrenia co iupared to healthy controls and patients with depression: Evidence from event— rela ted fI RI Henrik Walter,a,* Ncnad Vasic,” Annett Hose,” Manfred Spitzer,” and Robert Christian V |
| Which perspectives can endophenotypes and biological markers offer in the early recognition of schizophrenia |
| J Neural Transm (20(17) DCII 10.1 (X171s(X)702-(X)7-0742-4 Printed in the Netherlands Rev mi' _Journal of_ Neural Transmission S'h ich pers Pitt I cs can endophenotypes and biological markers oiler in the early recognition of schizophrenia? S. Bender'2'3, NI. Wishrod2'4, K Resch' ‘Cenue for |
| Verification of proposed peripheral biomarkers in mononuclear cells of individuals with schizophrenia |
| Available online at www.sciencedirect.com ELSE VI ER ‘‘ ScienceDi rect Journal of Psdjatrjc Research xxx (2007) xxx-xxx JOURNAL OF PsY(:HIA1 R1C ft ESEARCH Ab%tracl www .elseiercom/hxato'jpsyclures Verification ol proposed peripheral biomarkers in mononuclear cells of md ivid ua is with schiz |
| Two macroscopic and microscopic brain imaging studies of human hippocampus in early Alzheimer's disease and schizophrenia research |
| SiAitSiR UN t%ltUlt liNt Statist, Mcd 2004; 23:327—350 i DOl 10. 1002.sim.1720i Two macroscopic and microscopic brain imaging studies of human hippocampus in early Alzheimer's disease and schizophrenia research Nicholas Lange”2'*'t, Stephen Lake3k Reisa Sperling45, John Brown7. Carol Routledge |
| Trends in psychiatric hospitalisation of people with schizophrenia-A register-based investigation over the last three decades |
| f MODEL SCHRES.03248; No of Pages II ELSEVI ER Available online at www.sciencedirectcorn ?1?' ‘ ScienceDirect Schizo?hrenia Rcscarch xx (2007) rn-rn SCHIZOPHRENIA RES [ARCH www.eLscvicr.onm.1wateJschr Trends in psychiatric hospitalisation of people with schizophrenia: A1s(ract A register-based inves |
| Tone duration mismatch negativity deficits predict impairment of executive function in schizophrenia |
| MODIL PNP-06780; Noof Pagcs S ELSEVIER Available online at www.scencedirectcom ‘‘ ScienceDirect Progrcas in Ncuro-P hopharirtology & Biological Psychiatry xx (2007) xsx-xxx In Nei.PsychopOiuco,gy & Bi&ogic Psycaby www.ckcvicr.com1ocatcJpibp Tone duration mismatch negativity deficits predic |