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The plasma levels of interleukin-12 in schizophrenia, major depression, and bipolar mania: effects of psychotropic drugs - [Y-K Kim1, I-B Suh2, H Kim1, C-S Han1, C-S Lim2, S-H Choi3 and J Licinio4]
Monoamine transporter gene structure and polymorphisms in relation to psychiatric and other complex disorders - [M K Hahn and R D Blakely]
Association study of the serotonin transporter promoter polymorphism and symptomatology and antidepressant response in major depressive disorders - [Y W-Y Yu1, S-J Tsai2,3, T-J Chen4, C-H Lin4 and C-J Hong2,3]
Post exercise hypotension is not mediated by the serotonergic system in borderline hypertensive individuals - [J R MacDonald, J M Rosenfeld, M A Tarnopolsky, C D Hogben, C S Ballantyne and J D MacDougall]
Fluoxetine and Sleep EEG: Effects of a Single Dose, Subchronic Treatment, and Discontinuation in Healthy Subjects - [Bernd Feige1 Ph.D, Ulrich Voderholzer1 MD, Dieter Riemann1 Ph.D, Professor, Ralf Dittmann2 MD, Ph.D, Fritz Hohagen1 MD, Professor and Mathias Berger1 MD, Professor]
Delayed pharmacological effects of antidepressants - [A Frazer1,2 and S Benmansour1]
Quantitative Analysis for Estimating Binding Potential of the Brain Serotonin Transporter With [11C]McN5652 - [Yoko Ikoma*,?,?, Tetsuya Suhara?,?, Hinako Toyama§, Tetsuya Ichimiya?,?, Akihiro Takano?,?, Yasuhiko Sudo?,?, Makoto Inoue?,?, Fumihiko Yasuno?,? and Kazutoshi Suzuki?,?]
Response☆ - [Pierre Blier, Julie Turcotte, Chantal H??bert, Guy Debonnel]
Neurobehavioral Effects of Interferon- in Cancer Patients: Phenomenology and Paroxetine Responsiveness of Symptom Dimensions - [Lucile Capuron1 Ph.D, Jane F Gumnick1 MD, Dominique L Musselman1,2 MD, David H Lawson2 MD, Andrea Reemsnyder1 BS, Charles B Nemeroff1,2 MD, Ph.D and Andrew H Miller1,2 MD]
Potential role of levocarnitine supplementation for the treatment of chemotherapy-induced fatigue in non-anaemic cancer patients - [F Graziano1, R Bisonni2, V Catalano3, R Silva2, S Rovidati4, E Mencarini4, B Ferraro4, F Canestrari4, A M Baldelli3, A De Gaetano5, P Giordani3, E Testa1 and V Lai1]
Association between decreased serum tryptophan concentrations and depressive symptoms in cancer patients undergoing cytokine therapy - [L Capuron1,2, A Ravaud3, P J Neveu1, A H Miller2, M Maes4 and R Dantzer1]
Early Changes in Prefrontal Activity Characterize Clinical Responders to Antidepressants - [Ian A Cook MD, Andrew F Leuchter MD, Melinda Morgan Ph.D, Elise Witte Ph.D, William F Stubbeman MD, Michelle Abrams RN, Susan Rosenberg MSN and Sebastian HJ Uijtdehaage Ph.D]
Nicotinic acetylcholine receptors as targets for antidepressants - [R D Shytle1,2,3,4,5,6,7, A A Silver2,3, R J Lukas8, M B Newman1,6, D V Sheehan7 and P R Sanberg1,2,3,4,5,6,7]
Antidepressant, anxiolytic and anorectic effects of a melanin-concentrating hormone-1 receptor antagonist - [Beth Borowsky, Margaret M. Durkin, Kristine Ogozalek, Mohammad R. Marzabadi, John DeLeon, Rainer Heurich, Harvey Lichtblau, Zoya Shaposhnik, Irena Daniewska, Thomas P. Blackburn, Theresa A. Branchek, Christophe Gerald, Pierre J. Vaysse, Carlos Forray]
Lithium Augmentation Increases the ACTH and Cortisol Response in the Combined DEX/CRH Test in Unipolar Major Depression - [Tom Bschor1 MD, Mazda Adli2 MD, Christopher Baethge2 MD, Uta Eichmann2, Marcus Ising3 Ph.D, Manfred Uhr3 MD, Sieglinde Modell3 MD, Heike Künzel3 MD, Bruno Müller-Oerlinghausen2 MD and Michael Bauer4 Ph.D, MD]
Selective Serotonin Reuptake Inhibitors Decrease Impulsive Behavior as Measured by an Adjusting Delay Procedure in the Pigeon - [Mary C Wolff MA and J David Leander Ph.D]
Function of the serotonin 5-hydroxytryptamine 2B receptor in pulmonary hypertension - [J.-M. LAUNAY1, P. HERVé2, K. PEOC’H1, C. TOURNOIS1, J. CALLEBERT1, C.G. NEBIGIL3,N. ETIENNE3, L. DROUET1, M. HUMBERT4,G.SIMONNEAU4 & L. MAROTEAUX3]
Atomoxetine Increases Extracellular Levels of Norepinephrine and Dopamine in Prefrontal Cortex of Rat: A Potential Mechanism for Efficacy in Attention Deficit/Hyperactivity Disorder - [Frank P Bymaster MS, Jason S Katner BS, David L Nelson Ph.D, Susan K Hemrick-Luecke MS, Penny G Threlkeld MS, John H Heiligenstein]
Treatment of mood disorders - [Charles B. Nemeroff & Michael J. Owens]
The Phosphodiesterase Type 4 Inhibitor, Rolipram, Enhances Glucocorticoid Receptor Function - [Andrew H Miller MD, Gerald J Vogt Ph.D and Bradley D Pearce Ph.D]
R-fluoxetine Increases Extracellular DA, NE, As Well As 5-HT in Rat Prefrontal Cortex and Hypothalamus: An in vivo Microdialysis and Receptor Binding Study - [Susanne Koch Ph.D, Kenneth W Perry MS, David L Nelson Ph.D, Richard G Conway MS, Penny G Threlkeld MS and Frank P Bymaster MS]
Acute SSRI Administration Affects the Processing of Social Cues in Healthy Volunteers - [C J Harmer1, Z Bhagwagar1, D I Perrett2, B A V?llm1, P J Cowen1 and G M Goodwin1]
PLASMA MEMBRANE MONOAMINE TRANSPORTERS: STRUCTURE, REGULATION AND FUNCTION - [Gonzalo E. Torres, Raul R. Gainetdinov & Marc G. Caron about the authors]
KNOCKOUTS MODEL THE 100 BEST-SELLING DRUGS—WILL THEY MODEL THE NEXT 100? - [Brian P. Zambrowicz & Arthur T. Sands about the authors]
Monoamine depletion in psychiatric and healthy populations: review - [L Booij1, A J W Van der Does1,2 and W J Riedel3,4,5]
Investigation of polymorphism in the MDR1 gene and antidepressant-induced mania - [V De Luca1, E Mundo1,2, J Trakalo1, G W H Wong1 and J L Kennedy1]
Hypothalamic–pituitary–adrenal(HPA) system activity in depression and infection with Borna disease virus and Chlamydia pneumoniae - [M Deuschle, L Bode, P Schnitzler, U Meyding-Lamad??, A Plesch, H Ludwig, B Hamann, I Heuser]
Affective disorders, antidepressant drugs and brain metabolism - [A Moretti, A Gorini and R F Villa]
Synergistic Action of 5-HT2A Antagonists and Selective Serotonin Reuptake Inhibitors in Neuropsychiatric Disorders - [Gerard J Marek1,*, Linda L Carpenter2, Christopher J McDougle3 and Lawrence H Price2]
Serotonin Transporter: A Potential Substrate in the Biology of Suicide - [David C Purselle and Charles B Nemeroff]
Norepinephrine but not Serotonin Reuptake Inhibitors Enhance Theta and Gamma Activity of the Septo-Hippocampal System - [Mihály Hajós1, William E Hoffmann1, Deborah D Robinson2, Jen H Yu2 and éva Hajós-Korcsok2]
Method of treatment must be specific - [.]
Antidepressant-Like Effect of Different Estrogenic Compounds in the Forced Swimming Test - [Erika Estrada-Camarena1,2, Alonso Fernández-Guasti1 and Carolina López-Rubalcava1]
Maintenance Efficacy of Divalproex in the Prevention of Bipolar Depression - [Laszlo Gyulai1, Charles L Bowden2, Susan L McElroy3, Joseph R Calabrese4, Frederick Petty5, Alan C Swann6, James C-Y Chou7,8, Adel Wassef6, Craig S Risch9, Robert M A Hirschfeld10, Charles B Nemeroff11, Paul E Keck Jr3, Dwight L Evans1 and Patricia J Wozn]
Duloxetine Increases Serotonin and Norepinephrine Availability in Healthy Subjects: A Double-Blind, Controlled Study - [Stephan A Chalon1, Luc-André Granier1, Fran?ois R Vandenhende1, Peter R Bieck2, Frank P Bymaster2, Melissa J Joliat2, Christine Hirth3 and William Z Potter2]
The Antidepressant Clomipramine Regulates Cortisol Intracellular Concentrations and Glucocorticoid Receptor Expression in Fibroblasts and Rat Primary Neurones - [Carmine M Pariante1, Abdul Hye2, Ritchie Williamson2, Andrew Makoff1, Simon Lovestone2 and Robert W Kerwin1]
THE BALANCING ACT - [.]
Higher Cortisol Levels Following Exposure to Traumatic Reminders in Abuse-Related PTSD - [Bernet M Elzinga1, Christian G Schmahl2, Eric Vermetten3, Richard van Dyck4 and J Douglas Bremner5,6,7]
Regulatory Effects of Reboxetine Treatment Alone, or Following Paroxetine Treatment, on Brain Noradrenergic and Serotonergic Systems - [Georgianna G Gould1, Marie-Christine Pardon1, David A Morilak1 and Alan Frazer1,2]
SSR181507, A Dopamine D2 Receptor Antagonist and 5-HT1A Receptor Agonist. I: Neurochemical and Electrophysiological Profile - [Yves Claustre1, Danielle De Peretti1, Philippe Brun3, Christiane Gueudet2, Nathalie Allouard1, Richard Alonso2, Jo?lle Lourdelet1, André Oblin1, Gabrielle Damoiseau1, Dominique Fran?on1, Marie-Fran?oise Suaud-Chagny3, Régis Steinberg2, Mireille Sevrin1,]
A Pilot Study of Risperidone, Olanzapine, and Haloperidol in Psychotic Youth: A Double-Blind, Randomized, 8-Week Trial - [Linmarie Sikich1, Robert M Hamer1,2, Robert A Bashford1, Brian B Sheitman1,3 and Jeffrey A Lieberman1,4]
Alterations in Central Neuropeptide Expression, Release, and Receptor Binding in Rats Bred for High Anxiety: Critical Role of Vasopressin - [Alexandra Wigger1, Mar M Sánchez2, Kenneth C Mathys2, Karl Ebner3, Elisabeth Frank1, Dong Liu1, Adelheid Kresse4, Inga D Neumann5, Florian Holsboer1, Paul M Plotsky2 and Rainer Landgraf1]
Demonstration of the Efficacy and Safety of a Novel Substance P(NK1) Receptor Antagonist in Major Depression - [Mark S Kramer1,2, Andrew Winokur3, Jeffrey Kelsey4, Sheldon H Preskorn5,6, Anthony J Rothschild7, Duane Snavely1, Kalyan Ghosh1, William A Ball1, Scott A Reines1, Dennis Munjack8, Jeffrey T Apter9, Lynn Cunningham10, Mitchel Kling11, Mohammed Bari12, Albe]
The -Opioid Receptor Agonist (+)BW373U86 Regulates BDNF mRNA Expression in Rats - [Mary M Torregrossa1, Ceylan Isgor2, John E Folk3, Kenner C Rice3, Stanley J Watson1,2 and James H Woods1,4]
Chronic Fluoxetine Treatment Partly Attenuates the Long-Term Anxiety and Depressive Symptoms Induced by MDMA ('Ecstasy') in Rats - [Murray R Thompson1, Kong M Li2, Kelly J Clemens1, Clint G Gurtman1, Glenn E Hunt3, Jennifer L Cornish1 and Iain S McGregor1]
Amygdala Volume Reductions in Pediatric Patients with Obsessive-Compulsive Disorder Treated with Paroxetine: Preliminary Findings - [Philip R Szeszko1,2, Shauna MacMillan3, Marjorie McMeniman1,2, Elisa Lorch3, Rachel Madden3, Jennifer Ivey3, S Preeya Banerjee3, Gregory J Moore3,4 and David R Rosenberg3,5]
Influence of SERTPR and STin2 in the serotonin transporter gene on the effect of selective serotonin reuptake inhibitors in depression: a systematic review - [K M Smits1, L J M Smits1, J S AG Schouten1, F F Stelma1, P Nelemans1 and M H Prins1]
Pharmacogenetics of antidepressants and antipsychotics: the contribution of allelic variations to the phenotype of drug response - [J Kirchheiner1, K Nickchen1, M Bauer2, M-L Wong3, J Licinio3, I Roots1 and J Brockm?ller4]
From Galactorrhea to Osteopenia: Rethinking Serotonin-Prolactin Interactions - [Ana B F Emiliano1,2 and Julie L Fudge1,3]
Spitzer sues drug giant for deceiving doctors - [Meredith Wadman]
British drug company to put data online as criticism mounts - [Jim Giles]
a question of silence - [.]
Expose your clinical thinking - [.]
Fatigue and cancer: causes, prevalence and treatment approaches - [L I Wagner1 and D Cella1]
Preferential 5-HT1A Autoreceptor Occupancy by Pindolol is Attenuated in Depressed Patients: Effect of Treatment or an Endophenotype of Depression? - [Eugenii A Rabiner1,2, Zubin Bhagwagar2,3, Roger N Gunn1,4, Philip J Cowen3 and Paul M Grasby2]
Gene-environment interaction analysis of serotonin system markers with adolescent depression - [T C Eley1, K Sugden1, A Corsico1, A M Gregory1, P Sham1, P McGuffin1, R Plomin1 and I W Craig1]
Age-Dependent Reductions in the Level of Glial Fibrillary Acidic Protein in the Prefrontal Cortex in Major Depression - [Xiaohong Si, Jose Javier Miguel-Hidalgo, Gillian O'Dwyer, Craig A Stockmeier and Grazyna Rajkowska]
DRUGS AS MATERIALS: VALUING PHYSICAL FORM IN DRUG DISCOVERY - [Colin R. Gardner, Christopher T. Walsh & ?rn Almarsson about the authors]
A Systematic Review of Antidepressant Placebo-Controlled Trials for Geriatric Depression: Limitations of Current Data and Directions for the Future - [Warren D Taylor and P Murali Doraiswamy]
Serotonin 1A Receptor Binding and Treatment Response in Late-Life Depression - [Carolyn Cidis Meltzer1,2,3, Julie C Price1, Chester A Mathis1, Meryl A Butters2, Scott K Ziolko1, Eydie Moses-Kolko2, Sati Mazumdar2,4, Benoit H Mulsant2, Patricia R Houck2, Brian J Lopresti1, Lisa A Weissfeld4 and Charles F Reynolds2,3,5]
A quantitative genomic expression analysis platform for multiplexed in vitro prediction of drug action - [E C Gunther1, D J Stone1,2, J M Rothberg1 and R W Gerwien1]
Sulpiride in Combination with Fluvoxamine Increases in vivo Dopamine Release Selectively in Rat Prefrontal Cortex - [Yukio Ago1, Shigeo Nakamura1, Akemichi Baba2 and Toshio Matsuda1]
Plasma Leptin and Adiposity During Antipsychotic Treatment of Schizophrenia - [Dan W Haupt1, Angela Luber1, Justin Maeda1, Angela K Melson1, Julie A Schweiger1 and John W Newcomer1]
Genetic polymorphisms of cytochrome P450 2D6 (CYP2D6): clinical consequences, evolutionary aspects and functional diversity - [M Ingelman-Sundberg1]
The catechol-O-methyltransferase Val108/158Met polymorphism affects short-term treatment response to mirtazapine, but not to paroxetine in major depression - [A Szegedi1, D Rujescu2, A Tadic3, M J Müller3, R Kohnen4, H H Stassen5 and N Dahmen3]
MR-based in vivo hippocampal volumetrics: 2. Findings in neuropsychiatric disorders - [E Geuze1,2, E Vermetten1,2 and J D Bremner3,4,5]
DEPRESSION, ANTIDEPRESSANTS AND SUICIDALITY: A CRITICAL APPRAISAL - [Julio Licinio & Ma-Li Wong about the authors]
Comparing the Effects of Antidepressants: Consensus Guidelines for Evaluating Quantitative Reviews of Antidepressant Efficacy - [Jeffery A Lieberman1, Joel Greenhouse2, Robert M Hamer3, K Ranga Krishnan4, Charles B Nemeroff5, David V Sheehan6, Michael E Thase7 and Martin B Keller8]
Effects of Acute Tryptophan Depletion on Negative Symptoms and Smoking Topography in Nicotine-Dependent Schizophrenics and Nonpsychiatric Controls - [Brian Hitsman1, Bonnie Spring2,3, William Wolf3,4, Regina Pingitore2,3, John W Crayton3,5 and Donald Hedeker6]
Relationship between brain serotonin transporter binding, plasma concentration and behavioural effect of selective serotonin reuptake inhibitors - [Kazufumi Hirano1, Ryohei Kimura1, Yumi Sugimoto2, Jun Yamada2, Shinya Uchida3, Yasuhiro Kato4, Hisakuni Hashimoto4 and Shizuo Yamada1]
THE RISE AND RISE OF DRUG DELIVERY - [Howard Rosen & Thierry Abribat about the authors]
A Sleep-related painful erections - [Gilles Karsenty, Esther Werth, Peter A Knapp, Armin Curt, Brigitte Schurch, Claudio L Bassetti]
Validation of [123I]-CIT SPECT to Assess Serotonin Transporters In Vivo in Humans: a Double-Blind, Placebo-Controlled, Crossover Study with the Selective Serotonin Reuptake Inhibitor Citalopram - [Maartje M L de Win1,2, Jan B A Habraken3, Liesbeth Reneman1, Wim van den Brink4, Gerard J den Heeten1 and Jan Booij3]
Reduced Density of Platelet-Binding Sites for [3H]Paroxetine in Remitted Bulimic Women - [Howard Steiger1,2,3, Jodie Richardson1,2, Mimi Israel1,2,3, N M K Ng Ying Kin2,3, Kenneth Bruce1,2,3, Sandra Mansour1,2 and Anne Marie Parent1,2]
PHARMACOKINETIC VARIABILITY OF ANTICANCER AGENTS - [Samir D. Undevia, Gonzalo Gomez-Abuin & Mark J. Ratain about the author]
MONITORING THE SAFETY OF LICENSED MEDICINES - [Alasdair Breckenridge, Kent Woods & June Raine about the authors]
Disease mongering and drug marketing - [Howard Wolinsky]
Effects of Acute and Long-Term Administration of Escitalopram and Citalopram on Serotonin Neurotransmission: an In Vivo Electrophysiological Study in Rat Brain - [Mostafa El Mansari1,3, Connie Sánchez2, Guy Chouvet1, Bernard Renaud1 and Nasser Haddjeri1]
DRUG RESISTANCE IN BRAIN DISEASES AND THE ROLE OF DRUG EFFLUX TRANSPORTERS - [Wolfgang L?scher & Heidrun Potschka about the authors]
THE ASCENT OF MOUSE: ADVANCES IN MODELLING HUMAN DEPRESSION AND ANXIETY - [John F. Cryan & Andrew Holmes about the authors]
THE DISCOVERY OF FLUOXETINE HYDROCHLORIDE (PROZAC) - [David T. Wong, Kenneth W. Perry & Frank P. Bymaster about the authors]
Association Study of a Monoamine Oxidase A Gene Promoter Polymorphism with Major Depressive Disorder and Antidepressant Response - [Younger W-Y Yu1, Shih-Jen Tsai2,3, Chen-Jee Hong2,3, Tai-Jui Chen4,5, Ming-Chao Chen6 and Chih-Wei Yang5]
Glutamatergic Dysfunction in OCD - [Kaushik Chakrabarty1, Sagnik Bhattacharyya2,5, Rita Christopher3 and Sumant Khanna4,5]
Antipanic Efficacy of Paroxetine and Polymorphism within the Promoter of the Serotonin Transporter Gene - [Giampaolo Perna1, Elisa Favaron1, Daniela Di Bella1, Riccardo Bussi1 and Laura Bellodi1]
A call for the creation of personalized medicine databases - [David Gurwitz1, Jeantine E. Lunshof2 and Russ B. Altman3 About the authors]
Neuropharmacology of 5-hydroxytryptamine - [A Richard Green1]
Neonatal Antidepressant Exposure has Lasting Effects on Behavior and Serotonin Circuitry - [Dorota Maciag1,4, Kimberly L Simpson2,4, David Coppinger3, Yuefeng Lu2, Yue Wang2, Rick C S Lin2 and Ian A Paul1,3]
Neurotransmitter transporters and their impact on the development of psychopharmacology - [Leslie Iversen1]
Serotonin Function in Panic Disorder: Important, But Why? - [Eduard Maron1 and Jakov Shlik2]
Loss of Serotonin Transporter Protein after MDMA and Other Ring-Substituted Amphetamines - [Tao Xie1, Liqiong Tong1, Michael W McLane1, George Hatzidimitriou1, Jie Yuan1, Una McCann2 and George Ricaurte1]
Blockade of 5-HT1A Receptors by ()-Pindolol Potentiates Cortical 5-HT Outflow, but not Antidepressant-Like Activity of Paroxetine: Microdialysis and Behavioral Approaches in 5-HT1A Receptor Knockout Mice - [Jean-Philippe Guilloux1, Denis J P David1, Bruno P Guiard1, Franck Chenu2, Christelle Repérant1, Miklos Toth3, Michel Bourin2 and Alain M Gardier1]
Pharmacokinetic Profile of Single and Repeated Oral Doses of MDMA in Squirrel Monkeys: Relationship to Lasting Effects on Brain Serotonin Neurons - [Annis Mechan1, Jie Yuan1, George Hatzidimitriou1, Rodney J Irvine2, Una D McCann3 and George A Ricaurte]
Animal models in urological disease and sexual dysfunction - [Gordon McMurray1, James H Casey1 and Alasdair M Naylor1]
Participation of the 5-HT1A Receptor in the Antidepressant-Like Effect of Estrogens in the Forced Swimming Test - [Erika Estrada-Camarena1, Alonso Fernández-Guasti2 and Carolina López-Rubalcava2]
The Proinflammatory Cytokines Interleukin-1beta and Tumor Necrosis Factor-Alpha Activate Serotonin Transporters - [Chong-Bin Zhu1, Randy D Blakely1,2,3 and William A Hewlett1,2]
The effectiveness of treatment for depression/depressive symptoms in adults with cancer: a systematic review - [S Williams1 and J Dale1]
Phencyclidine-Induced Cognitive Deficits in Mice are Improved by Subsequent Subchronic Administration of Fluvoxamine: Role of Sigma-1 Receptors - [Kenji Hashimoto1, Yuko Fujita1 and Masaomi Iyo2]
Verdict on clinical trials registries? Good, but must do better - [Meredith Wadman]
Methylphenidate ('Ritalin') can Ameliorate Abnormal Risk-Taking Behavior in the Frontal Variant of Frontotemporal Dementia - [Shibley Rahman1, Trevor W Robbins2, John R Hodges3,4, Mitul A Mehta5, Peter J Nestor3, Luke Clark2 and Barbara J Sahakian1]
ACNP Task Force Report on SSRIs and Suicidal Behavior in Youth - [.]
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