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SSR181507, A Dopamine D2 Receptor Antagonist and 5-HT1A Receptor Agonist. I: Neurochemical and Electrophysiological Profile - [Yves Claustre1, Danielle De Peretti1, Philippe Brun3, Christiane Gueudet2, Nathalie Allouard1, Richard Alonso2, Jo?lle Lourdelet1, André Oblin1, Gabrielle Damoiseau1, Dominique Fran?on1, Marie-Fran?oise Suaud-Chagny3, Régis Steinberg2, Mireille Sevrin1,]
Impaired response to amphetamine and neuronal degeneration in the nucleus accumbens of autoimmune MRL-lpr mice - [Anderson KK, Ballok DA, Prasad N, Szechtman H, Sakic B.]
High affinity [3H]imipramine and [3H]paroxetine binding sites in suicide brains - [P. Rosel, B. Arranz, J. Vallejo, M. Oros, J. M. Menchón, P. Alvarez, M. A. Navarro]
Peripheral Markers of Serotonergic and Noradrenergic Function in Post-Pubertal, Caucasian Males with Autistic Disorder - [Jan Croonenberghs1 MD, Laure Delmeire2 MD, Robert Verkerk3 Ph.D, Ai-hua Lin2,3 MD, MSci, Anisa Meskal5 Ph.D, Hugo Neels5 Ph.D, Marc Van der Planken6 MD, Ph.D, Simon Scharpe3 Ph.D, Dirk Deboutte1 MD, Ph.D, Greet Pison4 Ph.D and Michael Maes2,7,8,9 MD, Ph.D]
Serotonergic and Noradrenergic Markers of Post-Traumatic Stress Disorder with and without Major Depression - [Michael Maes1,2,3 MD, Ph.D, Ai-hua Lin1 MD, MSci, Robert Verkerk4 Ing, Laure Delmeire1 MD, An Van Gastel MD, Marc Van der Planken5 MD, Ph.D and Simon Scharpé4 Ph.D]
Co-catalyzed reductive cyclization of azido and cyano substituted α,β-unsaturated esters with NaBH4: enantioselective synthesis of ?-baclofen and ?-rolipram - [Abhimanyu S. Paraskar and Arumugam Sudalai]
Social anxiety disorder assessment and pharmacological management - [I. Figueira, R. Jacques]
Social phobia: diagnosis and epidemiology, neurobiology and pharmacology, comorbidity and treatment - [N. Brunello, J. A. den Boer, L. L. Judd, S. Kasper, J. E. Kelsey, M. Lader, Y. Lecrubier, J. P. Lepine, R. B. Lydiard, J. Mendlewicz, et al.]
Social anxiety disorder under scrutiny - [Jonathan R.T. Davidson, M.D. * AD:Department of Psychiatry and Behavioral Science, Duke University Medical Center, Durham, North Carolina]
Pharmacological approaches to smoking cessation - [Mitrouska I, Bouloukaki I, Siafakas NM.]
Antidepressant treatment of the depressed patient with insomnia - [Thase ME.]
EEG correlates of acute and chronic paroxetine treatment in depression - [Verner Knott, Colleen Mahoney, Sidney Kennedy and Kenneth Evans]
Trends in the Development of New Antidepressants. Is there a Light at the End of the Tunnel? - [Pal Pacher, Valeria Kecskemeti]
Antidepressants: past, present and future - [Jerzy Vetulani and Irena Nalepa]
A Single Dose of the Serotonin Neurotransmission Agonist Paroxetine Enhances Motor Output: Double-Blind, Placebo-Controlled, fMRI Study in Healthy Subjects - [Isabelle Loubinoux, Jérémie Pariente, Kader Boulanouar, Christophe Carel, Claude Manelfe, Olivier Rascol, Pierre Celsis and Fran?ois Chollet]
Manifestations of West Nile neuroinvasive disease - [Sejvar JJ, Marfin AA.]
Paroxetine influences respiration in rats: implications for the treatment of panic disorder - [Marie Olsson, Kristina Annerbrink, Finn Bengtsson, Jan Hedner and Elias Eriksson]
Paroxetine influences respiration in rats, Implications for the treatment of panic disorder - [Olsson M, Annerbrink K, Bengtsson F, Hedner J, Eriksson E]
The effects of antidepressant drug treatments on activator protein-1 binding activity in the rat brain - [Tatsuji Tamura, Shigeru Morinobu, Yasumasa Okamoto, Ariyuki Kagaya and Shigeto Yamawaki]
Effects of Hypericum perforatum and paroxetine in the mouse defense test battery - [Vanessa Beijamini and Roberto Andreatini]
The Corticosteroid Receptor Hypothesis of Depression - [Florian Holsboer MD, Ph.D]
Implication of abnormal epigenetic patterns for human diseases - [Santos-Rebou?as CB, Pimentel MM.]
Paroxetine in the treatment of severe non-dermatological pruritus: a randomized, controlled trial - [Zbigniew Zylicz, Malgorzata Krajnik, Adriaan Alistar van Sorge and Massimo Costantini]
Antidepressant-like effects in various mice strains in the tail suspension test - [Nadège Ripoll, Denis Joseph Paul David, Eric Dailly, Martine Hasco?t and Michel Bourin]
Effects of Endogenous Neurotransmitters on the in vivo Binding of Dopamine and 5-HT Radiotracers in Mice - [Onarae V Rice1 MA, S John Gatley1 Ph.D, Ji Shen1 Ph.D, Craig L Huemmer1 BS, Renata Rogoz1 Ph.D, Onofre T DeJesus2 Ph.D, Nora D Volkow1 MD and Andrew N Gifford1 Ph.D]
Separation of five recently commercialized selective serotonin reuptake inhibitor antidepressants by capillary electrophoresis - [Vincenzo Pucci 1, Salvatore Fanali 2, Cesare Sabbioni 1, Maria Augusta Raggi * AD:1University of Bologna, Department of Pharmaceutical Sciences, Via Belmeloro 6, 40126 Bologna, Italy; Fax: +39 051 20997342National Council of Research, Institute of Chemist]
Local 5,7-Dihydroxytryptamine Lesions of Rat Amygdala: Release of Punished Drinking, Unaffected Plus-Maze Behavior and Ethanol Consumption - [Wolfgang Sommer1 MD, Ph.D, Christian Moller1 MD, Ph.D, Lisa Wiklund1 BSc, Annika Thorsell1 Ph.D, Roberto Rimondini1 Ph.D, Hans Nissbrandt2 MD, Ph.D and Markus Heilig1 MD, Ph.D]
Are behavioral problems in childhood and adolescence associated with bipolar disorder in early adulthood - [Endrass J, Vetter S, Gamma A, Gallo WT, Rossegger A, Urbaniok F, Angst J.]
Involvement of 5-HT2C receptors in the anti-immobility effects of antidepressants in the forced swimming test in mice - [Florence Clenet, Anouk De Vos and Michel Bourin]
The Gerbil Elevated Plus-Maze I: Behavioral Characterization and Pharmacological Validation - [Geoffrey B Varty, Cynthia A Morgan, Mary E Cohen-Williams, Vicki L Coffin, Galen J Carey]
Sleep in obsessive compulsive disorder:Polysomnographic studies under baseline conditions and after experimentally induced serotonin deficiency - [Voderholzer U, Riemann D, Huwig-Poppe C, Kuelz AK, Kordon A, Bruestle K, Berger M, Hohagen F.]
Association analysis of the chromosome 4p15-p16 candidate region for bipolar disorder and schizophrenia - [Christoforou A, Le Hellard S, Thomson PA, Morris SW, Tenesa A, Pickard BS, Wray NR, Muir WJ, Blackwood DH, Porteous DJ, Evans KL.]
Serotonin, 5-hydroxyindoleacetic acid and serotonin transporter in blood peripheral lymphocytes of patients with generalized anxiety disorder - [E. Hernández, S. Lastra, M. Urbina, I. Carreira and L. Lima]
Enzymatic alkoxycarbonylation reactions on the intermediate in the synthesis of (?)-paroxetine, trans-N-benzyloxycarbonyl-4-(4′-fluorophenyl)-3-hydroxymethylpiperidine - [Gonzalo de Gonzalo, Rosario Brieva, Víctor M. Sánchez, Miguel Bayod and Vicente Gotor]
Decreased Neuroendocrine Responses to Meta-Chlorophenylpiperazine (m-CPP) but Normal Responses to Ipsapirone in Marathon Runners - [Andreas Broocks1 MD, Tim Meyer5 MD, Annette George2 MD, Ursula Hillmer-Vogel4 MD, Detlef Meyer1 MD, Borwin Bandelow1 MD, G?ran Hajak1 MD, Uwe Bartmann1 Ph.D, Christoph H Gleiter3 MD and Eckart Rüther1 MD]
Drug sales in four European countries still differ - [Silvio Garattini, Livio Garattini]
Inhibition of phenytoin hydroxylation in human liver microsomes by several selective serotonin re-uptake inhibitors - [M. H. Nelson, A. K. Birnbaum and R. P. Remmel]
Clinical implications of pharmacogenetics of antidepressants - [Koichi Otani, Kazuo Mihara, Norio Yasui-Furukori, Akihito Suzuki, Tsuyoshi Kondo and Sunao Kaneko]
Pharmacokinetic drug interactions of new antidepressants: a review of the effects on the metabolism of other drugs. - [Richelson E]
Serum disposition of sertraline, N-desmethylsertraline and paroxetine: a pharmacokinetic evaluation of repeated drug concentration measurements during 6 months of treatment for major depression - [Margareta Reis 1 2 *, Anna ?berg-Wistedt 3, Hans ?gren 4, Peter H?glund 2, Ann-Charlotte ?kerblad 5, Finn Bengtsson 5 AD:1Department of Medicine and Care, Division of Clinical Pharmacology, Faculty of Health Sciences, Link?ping University, Link?ping, Swed]
Ionic interactions in the Drosophila serotonin transporter identify it as a serotonin channel - [Christina I. Petersen, Louis J. DeFelice]
2-((2-((dimethylamino)methyl)phenyl)thio)-5-iodophenylamine (ADAM): an improved serotonin transporter ligand - [Shunichi Oya, Seok-Rye Choi, Catherine Hou, Mu Mu, Mei-Ping Kung, Paul D. Acton, Michael Siciliano and Hank F. Kung]
Characterization of serotonin transporter in blood lymphocytes of rats. Modulation by in vivo administration of mitogens - [Nemesio Cede?o, Mary Urbina, Francisco Obregón and Lucimey Lima]
Decrease of Serotonin Transporters in Blood Platelets after Epileptic Seizures - [Aroldo Cupello, Emilio Favale, Daniela Audenino, Simona Scarrone, Stefania Gastaldi, Claudio Albano]
Serotonin transporter mRNA expression in peripheral leukocytes of patients with major depression before and after treatment with paroxetine - [Jun-ichi Iga, Shu-ichi Ueno, Ken Yamauchi, Ikuyo Motoki, Sumiko Tayoshi, Koshi Ohta, Hongwei Song, Kyoko Morita, Kazuhito Rokutan and Tetsuro Ohmori]
Antipanic Efficacy of Paroxetine and Polymorphism within the Promoter of the Serotonin Transporter Gene - [Giampaolo Perna1, Elisa Favaron1, Daniela Di Bella1, Riccardo Bussi1 and Laura Bellodi1]
Placebo-Controlled Trial Comparing Intermittent and Continuous Paroxetine in Premenstrual Dysphoric Disorder - [Mikael Landén1, Hans Nissbrandt2, Christer Allgulander3, Karin S?rvik4, Christina Ysander4 and Elias Eriksson2,4]
Pregnancy outcomes following exposure to serotonin reuptake inhibitors: a meta-analysis of clinical trials - [Roja Rahimi, Shekoufeh Nikfar and Mohammad Abdollahi]
Differential brain metabolic predictors of response to paroxetine in obsessive-compulsive disorder versus major depression - [Sanjaya Saxena, Arthur L Brody, Matthew L Ho, Narineh Zohrabi, et al]
Antidepressant-induced regulation of 5-HT1b mRNA in rat dorsal raphe nucleus reverses rapidly after drug discontinuation - [J.P. Anthony, T.J. Sexton, J.F. Neumaier * Department of Psychiatry and Behavioral Sciences and Harborview Medical Center, University of Washington, Seattle]
The effect of 5-hydroxytryptamine 3A and 3B receptor genes on nausea induced by paroxetine - [T Sugai1, Y Suzuki1, K Sawamura1, N Fukui1, Y Inoue2 and T Someya1]
Higher plasma 5-hydroxyindoleacetic acid levels are associated with SSRI-induced nausea. - [Ueda N, Yoshimura R, Shinkai K, Sakata Y, Nakamura J]
Resource use and costs associated with patients treated for depression in primary care - [Sobocki P, Ekman M, Agren H, Krakau I, Runeson B, M?rtensson B, J?nsson B.]
Efficacy of Venlafaxine ER in patients with social anxiety disorder: a double-blind, placebo-controlled, parallel-group comparison with paroxetine - [Christer Allgulander 1 *, Richard Mangano 2, Jun Zhang 2, Alv A. Dahl 3, Ulla Lepola 4, Ingemar Sj?din 5, Gerard Emilien 6, for the SAD 388 Study Group AD:1Karolinska Institutet, The Neurotec Department, Section of Psychiatry, Stockholm, Sweden2Wyeth Rese]
Placental passage of antidepressant medications. - [Hendrick V, Stowe ZN, Altshuler LL, Hwang S, Lee E, Haynes D]
Measuring Anxiety in Patients with Schizophrenia - [Seedat S, Fritelli V, Oosthuizen P, Emsley RA, Stein DJ.]
Double-blind, placebo-controlled comparison of imipramine and paroxetine in the treatment of bipolar depression. - [Nemeroff CB, Evans DL, Gyulai L, Sachs GS, Bowden CL, Gergel IP, Oakes R, Pitts CD]
Comparison of (+)-(11)C-McN5652 and (11)C-DASB as serotonin transporter radioligands under various experimental conditions. - [Szabo Z, McCann UD, Wilson AA, Scheffel U, Owonikoko T, Mathews WB, Ravert HT, Hilton J, Dannals RF, Ricaurte GA]
Effect of paroxetine on thyroid hormone levels in severely depressed patients. - [Konig F, Hauger B, von Hippel, Wolfersdorf M, Kaschka WP]
Animal models in urological disease and sexual dysfunction - [Gordon McMurray1, James H Casey1 and Alasdair M Naylor1]
Selective serotonin reuptake inhibitors and withdrawal symptoms: a review of the literature - [Fran?ois Therrien 1, John S. Markowitz 2 * AD:1Faculté de Pharmacie, Université de Montréal, 2900, Boul. Edouard-Montpetit, C.P. 6128, succursale A, Montréal, Québec, Canada, H3C 3J72Department of Pharmacy Practice, Institute of Psychiatry, Medical U]
Role of 5-HT1A and 5-HT1B Receptors in the Mediation of Behavior in the Forced Swim Test in Mice - [Michael F O]
Anger experience and expression across the anxiety disorders - [Moscovitch DA, McCabe RE, Antony MM, Rocca L, Swinson RP.]
The association of insomnia with anxiety disorders and depression-Exploration of the direction of risk - [Johnson EO, Roth T, Breslau N.]
Methylenedioxymethamphetamine-induced suppression of interleukin-1β and tumour necrosis factor-α is not mediated by serotonin - [Thomas J. Connor, Michael C. Dennedy, Andrew Harkin and John P. Kelly]
Electrophysiological Evidence for the Tonic Activation of 5-HT1A Autoreceptors in the Rat Dorsal Raphe Nucleus - [Nasser Haddjeri1, Normand Lavoie2 and Pierre Blier2]
Reduction in serotonin synthesis following acute and chronic treatments with paroxetine, a selective serotonin reuptake inhibitor, in rat brain: an autoradiographic study with α-[14C]methyl--tryptophan - [Fumitaka Yamane, Hidehiko Okazawa, Pierre Blier and Mirko Diksic]
1-(m-Chlorophenyl)piperazine (mCPP) Dissociates In Vivo Serotonin Release from Long-Term Serotonin Depletion in Rat Brain - [Michael H Baumann Ph.D, Mario A Ayestas BS, Christina M Dersch MS and Richard B Rothman MD, Ph.D]
Cellular determinants of reduced adaptability of the aging brain: neurotransmitter utilization and cell signaling responses after MDMA lesions - [T. A. Slotkin, F. J. Seidler and S. F. Ali]
The Kutcher Adolescent Depression Scale: Assessment of Its Evaluative Properties over the Course of an 8-Week Pediatric Pharmacotherapy Trial - [Sarah J. Brooks, Stanley P. Krulewicz, Stan Kutcher]
Effect of nortriptyline and paroxetine on extrapyramidal signs and symptoms - [David C Mamo, Robert A Sweet, Benoit H Mulsant, Bruce G Pollock, et al.]
A twelve-week, double-blind, Randomized comparison of nortriptyline and paroxetine in older depressed inpatients and outpatients - [Benoit H Mulsant, Bruce G Pollock, Robert Nebes, Mark D Miller, et al.]
Blockade of 5-HT1A Receptors by ()-Pindolol Potentiates Cortical 5-HT Outflow, but not Antidepressant-Like Activity of Paroxetine: Microdialysis and Behavioral Approaches in 5-HT1A Receptor Knockout Mice - [Jean-Philippe Guilloux1, Denis J P David1, Bruno P Guiard1, Franck Chenu2, Christelle Repérant1, Miklos Toth3, Michel Bourin2 and Alain M Gardier1]
Treatment-emergent behavioural side effects with selective serotonin re-uptake inhibitors in adults with learning disabilities - [A. B. Biswas 1 *, S. Bhaumik 1, D. Branford 2 AD:1University of Leicester, & Leicestershire and Rutland Healthcare NHS Trust, Frith Hospital, Groby Road, Leicester LE3 9QF, UK2Southern Derbyshire Mental Health Trust, Kingsway Hospital, Derby DE22 3LZ, UK]
Efficacy and tolerability of escitalopram in 12- and 24-week treatment of social anxiety disorder: Randomised, double-blind, placebo-controlled, fixed-dose study - [Malcolm Lader, M.D. 1 *, Karina Stender, Ph.D. 2, Vera Bürger, M.Sc. 3, Rico Nil, Ph.D. 4 AD:1Institute of Psychiatry, University of London, London, United Kingdom2H. Lundbeck A/S, Copenhagen, Denmark3Lundbeck Austria GmbH, Vienna, Austria4Lundbeck (Swit]
Occupancy of serotonin transporters by paroxetine and citalopram during treatment of depression: A [11C] DASB PET imaging study - [Jeffrey H Meyer, Alan A Wilson, Nathalie Ginovart, Verdell Goulding, et al]
Effects of continuous administration of paroxetine on ligand binding site and expression of serotonin transporter protein in mouse brain - [Kazufumi Hirano, Takahiro Seki, Norio Sakai, Yasuhiro Kato, Hisakuni Hashimoto, Shinya Uchida and Shizuo Yamada]
Separation of new antidepressants and their metabolites by micellar electrokinetic capillary chromatography - [L. Labat, M. Deveaux, P. Dallet and J. P. Dubost]
Paroxetine-induced apoptosis in human osteosarcoma cells: Activation of p38 MAP kinase and caspase-3 pathways without involvement of [Ca2+]i elevation - [Chiang-Ting Chou, Shiping He and Chung-Ren Jan]
Paroxetine versus citalopram treatment of pathological crying after brain injury - [Ulrich Muller, Toshiya Murai, Thomas Bauer-Wittmund, D. Yves Von Cramon]
Which selective serotonin reuptake inhibitor works best? - [Robert K Schneider, James L Levenson]
SSRIs and Ejaculation A Double-Blind, Randomized, Fixed-Dose Study With Paroxetine and Citalopram - [Waldinger MD, Zwinderman AH, Olivier B.]
Effects of chronic treatment with fluvoxamine and paroxetine during adolescence on serotonin-related behavior in adult male rats - [Trynke R. de Jong, Liselore J.A.E. Snaphaan, Tommy Pattij, Jan G. Veening, Marcel D. Waldinger, Alexander R. Cools and Berend Olivier]
Vardenafil reverses erectile dysfunction induced by paroxetine in rats - [J Angulo, E Bischoff, S Gabancho, P Cuevas, I Sáenz de Tejada]
α2-Adrenergic agonists antagonise the anxiolytic-like effect of antidepressants in the four-plate test in mice - [Fabienne Massé, Martine Hasco?t and Michel Bourin]
Do selective serotonin re-uptake inhibitors enhance the efficacy of very brief cognitive behavioral therapy for panic disorder? A pilot study - [Murray B. Stein, G. Ron Norton, John R. Walker, Mariette J. Chartier and Roger Graham]
Neonatal withdrawal syndrome after in utero exposure to selective serotonin reuptake inhibitors - [H. Nordeng, R. Lindemann, K. V. Perminov, . Reikvam1]
Once-daily high-dose pindolol for SSRI-refractory depression - [Kenneth N. Sokolski, Janet C. Conney, Brenda J. Brown and Edward M. DeMet]
High vs Low Anxiety-Related Behavior Rats: An Animal Model of Extremes in Trait Anxiety - [Rainer Landgraf, Alexandra Wigger]
Effect of different 5-HT1A receptor antagonists in combination with paroxetine on expression of the immediate–early gene Arc in rat brain - [R. Tordera, Q. Pei, M. Newson, K. Gray, M. Sprakes and T. Sharp]
Response selection in schizophrenia - [Pellizzer G, Stephane M.]
Normal Personality Characteristics in Schizophrenia A Review of the Literature Involving the FFM - [Dinzeo TJ, Docherty NM.]
Antipsychotics inhibit TREK but not TRAAK channels - [Susanne Thümmler, Fabrice Duprat and Michel Lazdunski]
Response styles among patients with minor depression and dysthymia in primary care - [College of Health Sciences, University of Texas at El Paso, 79902, USA. schmaling@utep.edu]
A Review of the Bioactivity of South African Herbal Teas Rooibos (Aspalathus linearis) and Honeybush (Cyclopia intermedia) - [McKay DL, Blumberg JB.]
Traitement d'une intoxication à l'hydroxychloroquine par circulation extracorporelle - [F. Mongenot, Y. Tessier Gonthier, F. Derderian, M. Durand and D. Blin]
Récepteurs 5-HT1B de la sérotonine et effets antidépresseurs des inhibiteurs de recapture sélectifs de la sérotonine5-HT1B receptors mediate the antidepressant effects of selective serotonin reuptake inhibitors. - [Alain M. Gardier, Anne-Cécile Trillat, Isabelle Malagié, Denis David, Martine Hasco?t, Marie-Claude Colombel, Pascale Jolliet, Christian Jacquot, René Hen and Michel Bourin]
Troubles dysphoriques prémenstruels : diagnostic et traitements médicamenteuxPremenstrual dysphoric disorder: diagnostic and pharmacological treatment - [G. Benjelloun and A. Pelissolo]
Expose your clinical thinking - [.]
DRUG RESISTANCE IN BRAIN DISEASES AND THE ROLE OF DRUG EFFLUX TRANSPORTERS - [Wolfgang L?scher & Heidrun Potschka about the authors]
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